12/31/2023 0 Comments Mn element toxicityThe bioaccumulation of Mn in the liver, gill, kidney, brain and muscle tissues, and experimental water at different intervals of 24, 48, 72 and 96 h were determined. The histopathology of the liver and gill were also changed due to exposure to Mn and Mn-NPs. ![]() Oxidative stress (catalase, superoxide dismutase, glutathione-s-transferase and glutathione peroxidase), stress biomarkers (lipid peroxidation, cortisol, heat shock protein, and blood glucose), lactate and malate dehydrogenase, alanine and aspartate aminotransferase, a neurotransmitter, glucose-6-phosphate dehydrogenase (G6PDH), ATPase, immune system biomarkers (NBT, total protein, albumin, globulin and A:G ratio) were altered with exposure to Mn and Mn-NPs. The acute definitive doses were applied to assess the effect of oxidative stress, glycolytic biomarkers, protein biomarkers, fish immunity, neurotransmitter, energy level, stress hormone and histopathology. The present investigation used five hundred forty-six fish, including range finding (216 fish) and definitive test (330 fish). The median lethal concentration (96-LC 50) of Mn alone (111.75 mg L −1) and along with high temperature (110.76 mg L −1), Mn-NPs alone (93.81 mg L −1) and with high temperature (34 ☌) (92.39 mg L −1) was determined in P. ![]() On the above information, an experiment was delineated to determine the lethal concentration of manganese (Mn) and manganese nanoparticles (Mn-NPs) alone and with high temperature (34 ☌) and its effect on various biochemical markers in Pangasianodon hypophthalmus. It is a still poorly studied in aquatic organisms, where it can be noticeably useful for dietary components and also found pollutant in aquatic environment at high concentrations. Manganese (Mn) is an essential element for humans and animals including, fish.
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